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CAUZE GENETICE

Cauze genetice de infertilitate la barbati

– microdeletii de cromozom Y (cromozomul masculin) – determina azoospermie non-obstructiva si reduce parametrii spermatici;
– translocatie cromozomiala (rearanjarea cromozomiala) – creste riscul de conceptie a unui copil cu anomalii (ex: sindrom Down) ; afectiune genetica asimptomatica;
– sindromul Klinefelter: absenta spermei, cantitati extrem de reduse de sperma, testicule mici, ferme, dezvoltarea mamara anormala, indivizi inalti si foarte slabi (barbatul are doi cromomi X si un cromozom Y in loc de 1 X si 1 Y) ;
– sindromul Kallmann (cunoscut si sub denumirea de hipogonadism hipotalamic) – o glanda a organismului nu produce suficienti hormoni, si astfel testiculele sunt mici si neproductive: inceput lent al pubertatii (identificat in parametrii spermatici scazuti), un simt al mirosului diminuat sau absent.
– anomalii congenitale generate de expunerea la DES (diethylstilbestrol).

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